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What is Microfragmentation?

Cutting Fat Down to Size

Just as hyaluronic acid fillers have been characterized by their cohesivity, viscosity, and elasticity into different products for different anatomical areas, adipose tissue can also be modified by cutting with ultra-sharp blades into specific thicknesses for different purposes, ether reconstructive, cosmetic, or restorative.


The use of mechanical processing means to fragment adipose tissue into various sizes.  This process breaks down larger fat clusters into smaller fragments, releasing regenerative cells, which result in different sized tissues that can be used for different applications. Additionally, through advanced devices and techniques, we can capture regenerative cells.


Microfragmented adipose injection tends to stay in the affected area, allowing your body to maximize the benefits of the reparative cells without being reabsorbed by the body.

Types of mechanical fragmenting

Microfragmentation preserves the native matrix of the adipose complex providing a healthier scaffold for reparative tissue-based procedures. There are four different mechanical actions for fragmenting fat—adinizing, emulsification, blunt screens, and distortion.


The mechanism of sharp cutting blades for the resizing of fat is the most efficient and least traumatic method for fat sizing. Adinizing is a gentler fragmenting process that reduces pressure on the adipose tissue giving practitioners resulting in increased cell viability and a more intact native matrix.

Why Fragmentation Matters

First to understand why fragmentation matters, it’s imperative to first understand that fat is a living tissue that plays a vital role in our bodies wound healing cascade. Different harvesting, purification, processing, and delivery methods plays a critical role in the success of regenerative fat procedures.
The Adinizer is an evolutionary living tissue management system that was developed with the purpose of handling fat in the most gentle and efficient manner for improved patient outcomes.

Consistency. Reproducibility. Better Patient Outcomes.

Let's Compare

Adinizing Vs. Emulsification

Adinized fat is not an emulsified fat. Adinizing and emulsification are different methods for processing / fragmenting of adipose tissue.  Adinizing cuts fat tissues while emulsification squeezes fat though forced pressure causing unnecessary damage to the adipose tissue complex.


Research is increasingly clear that processing methods may play a critical role in fat graft survival.  As basic science on the adipose tissue complex has become better understood it’s widely accepted that pressure exerted during processing can have a negative impact on cell survival. 


The Adinizer cutting-blade wheels offer a gentler and more precise way to manage living adipose tissues by displacing the fat across a wider surface area. The resulting fat contains better, healthier, and still-alive adipocytes, along with significantly more regenerative stromal cells and extracellular matrix (ECM).


  • Minimal Force
  • 3-5 passes per sizer – 9-15 total
  • Saves Time
  • Less Damage to Native Tissue
  • Consistent and Even Resizing
  • Mechanism of Action = Cutting


  • Excessive blunt, pressurized force
  • 30+ Passes per sizer – 90+ total
  • Long processing times
  • More damage to native tissue
  • Not able to accurately re-size
  • Mechanism of Action = Forced Pressure